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Multiple Choice
Which of the following cell organelles is a good target for antibacterial drugs?
A
Nucleus
B
Mitochondrion
C
Golgi apparatus
D
Ribosome
Verified step by step guidance
1
Understand the role of ribosomes in cells: Ribosomes are responsible for protein synthesis in both prokaryotic and eukaryotic cells. They translate messenger RNA (mRNA) into polypeptide chains, which then fold into functional proteins.
Recognize the difference between prokaryotic and eukaryotic ribosomes: Prokaryotic ribosomes (found in bacteria) are 70S, composed of 50S and 30S subunits, whereas eukaryotic ribosomes are 80S, composed of 60S and 40S subunits. This difference is crucial for targeting bacterial ribosomes without affecting human cells.
Identify why ribosomes are a good target for antibacterial drugs: Since bacterial ribosomes differ structurally from eukaryotic ribosomes, drugs can be designed to specifically inhibit bacterial protein synthesis without harming human cells.
Explore examples of antibiotics targeting ribosomes: Many antibiotics, such as tetracyclines and aminoglycosides, work by binding to bacterial ribosomes and disrupting protein synthesis, effectively killing or inhibiting bacterial growth.
Consider the implications of targeting ribosomes: While targeting ribosomes is effective, it is important to consider potential resistance mechanisms bacteria might develop, such as modifying ribosomal RNA or proteins to prevent drug binding.