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Multiple Choice
Which of the following events in translation is the first to occur in eukaryotes?
A
Attachment of the large ribosomal subunit
B
Termination of translation at a stop codon
C
Binding of the small ribosomal subunit to the mRNA
D
Formation of the peptide bond between amino acids
Verified step by step guidance
1
Understand the process of translation in eukaryotes, which involves the synthesis of proteins from mRNA. Translation occurs in three main stages: initiation, elongation, and termination.
Focus on the initiation stage, which is the first step in translation. During initiation, the components necessary for translation assemble on the mRNA strand.
Identify the key components involved in the initiation of translation: the mRNA, the small ribosomal subunit, the initiator tRNA, and various initiation factors.
Recognize that the first event in the initiation stage is the binding of the small ribosomal subunit to the mRNA. This step is crucial as it sets the stage for the rest of the translation process.
Note that after the small ribosomal subunit binds to the mRNA, the initiator tRNA carrying methionine binds to the start codon on the mRNA, followed by the attachment of the large ribosomal subunit, completing the formation of the functional ribosome ready for elongation.