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Multiple Choice
Which of the following is a way that neuromodulators can alter synaptic transmission?
A
By changing the sensitivity of postsynaptic receptors
B
By permanently blocking neurotransmitter release
C
By converting neurotransmitters into hormones
D
By directly generating action potentials in the postsynaptic neuron
Verified step by step guidance
1
Understand the role of neuromodulators: Neuromodulators are substances that influence the activity of neurons by modulating synaptic transmission, rather than directly initiating action potentials.
Analyze the first option: 'By changing the sensitivity of postsynaptic receptors.' Neuromodulators can alter the responsiveness of postsynaptic receptors to neurotransmitters, making them more or less sensitive to signals.
Evaluate the second option: 'By permanently blocking neurotransmitter release.' Neuromodulators typically do not permanently block neurotransmitter release; their effects are usually temporary and reversible.
Consider the third option: 'By converting neurotransmitters into hormones.' Neuromodulators do not convert neurotransmitters into hormones; neurotransmitters and hormones are distinct types of signaling molecules.
Review the fourth option: 'By directly generating action potentials in the postsynaptic neuron.' Neuromodulators do not directly generate action potentials; they influence the conditions under which action potentials may occur by modulating synaptic activity.