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Multiple Choice
What is the first step in the anaerobic glycolysis process?
A
Conversion of pyruvate to lactate
B
Oxidation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate
C
Cleavage of fructose-1,6-bisphosphate into two triose phosphates
D
Phosphorylation of glucose to form glucose-6-phosphate
Verified step by step guidance
1
Understand that glycolysis is the metabolic pathway where glucose is broken down to produce energy, and anaerobic glycolysis occurs without oxygen.
Recognize that the first step in glycolysis involves the phosphorylation of glucose, which is the addition of a phosphate group to glucose to form glucose-6-phosphate.
Learn that this phosphorylation reaction is catalyzed by the enzyme hexokinase (or glucokinase in the liver), and it requires ATP as the phosphate donor.
Understand the importance of this step: it traps glucose inside the cell and prepares it for further breakdown in subsequent steps of glycolysis.
Note that this step is irreversible under physiological conditions, making it a key regulatory point in glycolysis.