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Multiple Choice
The beginning of anaphase is indicated by which of the following processes?
A
Condensation of chromatin into visible chromosomes
B
Separation of sister chromatids at the centromere
C
Alignment of chromosomes along the metaphase plate
D
Disappearance of the nuclear envelope
Verified step by step guidance
1
Understand the context of the question: Anaphase is a stage in mitosis, a process of cell division. It is important to know the sequence of events in mitosis to identify the correct process associated with anaphase.
Recall the stages of mitosis: Prophase, Metaphase, Anaphase, and Telophase. Each stage has distinct characteristics. For example, chromatin condensation occurs in prophase, alignment of chromosomes happens in metaphase, and the nuclear envelope disappears during prophase.
Focus on anaphase: The hallmark of anaphase is the separation of sister chromatids. This occurs when the proteins holding the chromatids together at the centromere are cleaved, allowing them to move toward opposite poles of the cell.
Eliminate incorrect options: Condensation of chromatin into visible chromosomes occurs in prophase, alignment of chromosomes along the metaphase plate happens in metaphase, and disappearance of the nuclear envelope occurs in prophase. These processes are not specific to anaphase.
Conclude that the correct answer is the separation of sister chromatids at the centromere, as this is the defining event of anaphase in mitosis.