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Multiple Choice
How does ATP synthase produce ATP during cellular respiration?
A
By directly transferring electrons from NADH to ADP
B
By utilizing the flow of protons down their electrochemical gradient to catalyze the conversion of ADP and inorganic phosphate into ATP
C
By hydrolyzing ATP into ADP and phosphate to release energy
D
By breaking down glucose into pyruvate and releasing ATP as a byproduct
Verified step by step guidance
1
Understand the role of ATP synthase: ATP synthase is an enzyme located in the inner mitochondrial membrane that plays a critical role in the production of ATP during cellular respiration.
Recognize the source of energy for ATP synthesis: ATP synthase utilizes the energy from the flow of protons (H⁺ ions) down their electrochemical gradient, which is established by the electron transport chain during oxidative phosphorylation.
Describe the proton gradient: The electron transport chain pumps protons from the mitochondrial matrix into the intermembrane space, creating a high concentration of protons outside the matrix. This gradient represents potential energy.
Explain the mechanism of ATP synthase: As protons flow back into the mitochondrial matrix through ATP synthase, the enzyme harnesses this energy to catalyze the conversion of ADP (adenosine diphosphate) and inorganic phosphate (Pi) into ATP (adenosine triphosphate).
Clarify why other options are incorrect: ATP synthase does not directly transfer electrons from NADH to ADP, hydrolyze ATP, or break down glucose into pyruvate. Its primary function is to utilize the proton gradient to synthesize ATP.