Multiple Choice
Which of the following statements best describes what happens to MPF (Maturation Promoting Factor) during mitosis?
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16. Cell Division
Control of the Cell Cycle
Multiple Choice
In the context of control of the cell cycle, what is the primary role of cyclins in a cell?
A
They function as membrane channels that control ion flux to trigger cytokinesis.
B
They bind to and activate cyclin-dependent kinases (CDKs) to regulate progression through specific cell-cycle phases.
C
They form the structural scaffold of the mitotic spindle to separate sister chromatids.
D
They act as DNA polymerases that replicate the genome during S phase.
Verified step by step guidance1
Understand that the cell cycle is regulated by a series of checkpoints and molecular signals to ensure proper cell division.
Recognize that cyclins are proteins whose levels fluctuate throughout the cell cycle, and they do not function as structural components or enzymes like DNA polymerases.
Know that cyclins primarily bind to cyclin-dependent kinases (CDKs), forming active complexes that phosphorylate target proteins to drive the cell cycle forward.
Identify that the activation of CDKs by cyclins is crucial for progression through specific phases of the cell cycle, such as the transition from G1 to S phase or G2 to M phase.
Conclude that the primary role of cyclins is to regulate the timing and order of cell cycle events by activating CDKs, rather than acting as membrane channels, structural spindle components, or DNA polymerases.
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