Multiple Choice
Which of the following acts as a control of cell division?
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16. Cell Division
Control of the Cell Cycle
Multiple Choice
In control of the cell cycle, the G2 checkpoint prevents the cell cycle from continuing into mitosis until which condition is met?
A
All chromosomes are aligned at the metaphase plate and attached to spindle microtubules.
B
DNA replication is complete and any DNA damage has been repaired.
C
Sister chromatids have separated and the nuclear envelope has fully re-formed.
D
The cell has reached a critical size and has sufficient nutrients and growth factor signaling to enter S phase.
Verified step by step guidance1
Identify the role of the G2 checkpoint in the cell cycle, which is to ensure the cell is ready to enter mitosis after DNA replication.
Understand that the G2 checkpoint specifically monitors whether DNA replication is complete and checks for any DNA damage that needs repair before mitosis begins.
Recognize that the alignment of chromosomes at the metaphase plate and attachment to spindle microtubules is a feature of the metaphase checkpoint, not the G2 checkpoint.
Note that sister chromatid separation and nuclear envelope reformation occur after mitosis, so these events are not controlled by the G2 checkpoint.
Recall that cell size and nutrient availability are typically assessed at the G1 checkpoint, which controls entry into the S phase, not at the G2 checkpoint.
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