Multiple Choice
In the context of control of the cell cycle, which proteins stimulate cell division by activating cyclin-dependent kinases (CDKs) to promote progression through checkpoints?
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16. Cell Division
Control of the Cell Cycle
Multiple Choice
In a typical eukaryotic cell cycle, how many major checkpoints are commonly described that regulate progression through the cycle?
A
1
B
4
C
3
D
2
Verified step by step guidance1
Understand that the eukaryotic cell cycle is regulated at specific points called checkpoints, which ensure the cell is ready to proceed to the next phase.
Identify the major checkpoints commonly described in the cell cycle: the G1 checkpoint (also called the restriction point), the G2 checkpoint, and the M checkpoint (spindle checkpoint).
Recognize that these three checkpoints monitor different critical events: G1 checks for DNA damage and cell size before DNA synthesis, G2 ensures DNA replication is complete and undamaged before mitosis, and the M checkpoint ensures proper chromosome attachment to the spindle before anaphase.
Conclude that the typical number of major checkpoints regulating the eukaryotic cell cycle is three.
Note that while other minor checkpoints or regulatory mechanisms exist, the three mentioned are the primary ones commonly referenced in cell biology.
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