Multiple Choice
During mitosis, what is the primary role of spindle fibers (microtubules) in the dividing cell?
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15. Cytoskeleton and Cell Movement
Microtubules and Cell Division
Multiple Choice
In mitosis, what is the primary role of spindle fibers (microtubules) during anaphase?
A
They synthesize new nuclear envelope membranes around the chromosomes.
B
They replicate the cell's DNA to ensure each daughter cell receives a complete genome.
C
They form a cleavage furrow by constricting actin and myosin to separate the cytoplasm.
D
They attach to kinetochores and pull sister chromatids toward opposite poles of the cell.
Verified step by step guidance1
Understand the phase of mitosis in question: anaphase is the stage where sister chromatids are separated and pulled toward opposite poles of the cell.
Recall the structure and function of spindle fibers, which are composed of microtubules originating from centrosomes (spindle poles).
Recognize that spindle fibers attach to chromosomes at specialized protein structures called kinetochores located on the centromere of each chromatid.
During anaphase, spindle fibers shorten by depolymerizing, generating the force needed to pull sister chromatids apart toward opposite poles.
Conclude that the primary role of spindle fibers during anaphase is to ensure accurate segregation of sister chromatids by attaching to kinetochores and pulling them to opposite poles, facilitating equal distribution of genetic material.
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