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Multiple Choice
Which of the following statements best describes a feature of digenic single nucleotide polymorphisms (d-SNPs)?
A
They are synonymous mutations that do not alter the amino acid sequence of a protein.
B
They involve the interaction of two different genes, where specific SNPs in both genes together influence a trait.
C
They refer to SNPs that are always located on the same chromosome and inherited together.
D
They are single nucleotide changes that occur within a single gene and independently affect phenotype.
Verified step by step guidance
1
Step 1: Understand what a single nucleotide polymorphism (SNP) is — a variation at a single position in a DNA sequence among individuals.
Step 2: Recognize that 'digenic' refers to involving two genes, so digenic SNPs imply interactions between SNPs located in two different genes.
Step 3: Differentiate between SNPs that act independently within a single gene and those that require interaction between two genes to influence a trait.
Step 4: Note that synonymous mutations do not change the amino acid sequence, but digenic SNPs focus on gene interactions rather than mutation type.
Step 5: Conclude that digenic SNPs best describe the scenario where specific SNPs in two different genes together influence a trait, highlighting gene-gene interaction.