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Multiple Choice
Which type of mutation stops the translation of an mRNA molecule?
A
Missense mutation
B
Frameshift mutation
C
Silent mutation
D
Nonsense mutation
Verified step by step guidance
1
Understand the process of translation, where the mRNA sequence is read in codons (sets of three nucleotides) to synthesize a protein.
Recognize that a mutation can alter the mRNA sequence, potentially changing the amino acid sequence of the resulting protein.
Identify that a nonsense mutation introduces a premature stop codon (such as UAA, UAG, or UGA) into the mRNA sequence.
Know that this premature stop codon causes the ribosome to stop translation early, resulting in a truncated and usually nonfunctional protein.
Contrast this with other mutation types: missense mutations change one amino acid, frameshift mutations shift the reading frame, and silent mutations do not change the amino acid sequence.