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Multiple Choice
Which type of mutation introduces a premature stop codon that terminates translation of the mRNA early?
A
Nonsense mutation
B
Silent (synonymous) mutation
C
In-frame insertion (adds 3 nucleotides)
D
Missense mutation
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Verified step by step guidance
1
Understand the types of mutations listed: Silent (synonymous) mutation, In-frame insertion, Missense mutation, and Nonsense mutation.
Recall that a silent mutation changes a codon but does not alter the amino acid sequence, so it does not affect the protein length or function significantly.
Know that an in-frame insertion adds nucleotides in multiples of three, which inserts extra amino acids but does not cause early termination of translation.
Recognize that a missense mutation changes one amino acid to another, potentially altering protein function but not causing early stop codons.
Identify that a nonsense mutation changes a codon to a stop codon, causing premature termination of translation and producing a truncated protein.