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Multiple Choice
Which of the following correctly matches a stage of genomic imprinting with its description?
A
Erasure: Imprints are reinforced during embryonic development.
B
Maintenance: Imprints are erased in somatic cells after fertilization.
C
Establishment: DNA methylation patterns are set during gametogenesis.
D
Establishment: Imprints are removed from both parental alleles in the zygote.
Verified step by step guidance
1
Understand the concept of genomic imprinting, which involves parent-specific gene expression regulated by epigenetic marks such as DNA methylation.
Identify the three main stages of genomic imprinting: Establishment, Erasure, and Maintenance.
Define the Establishment stage as the process during gametogenesis when DNA methylation patterns (imprints) are set on the parental alleles.
Define the Erasure stage as the removal of existing imprints, typically occurring in primordial germ cells to reset imprinting marks for the next generation.
Define the Maintenance stage as the preservation of established imprints during embryonic development and cell division, ensuring parent-specific expression is retained.