Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

8. DNA Replication

Overview of DNA Replication

Genetics

8. DNA Replication

Overview of DNA Replication

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Multiple Choice

Human genome (DNA) researchers have discovered that:

DNA replication in humans is semi-conservative, with each new DNA molecule containing one original and one newly synthesized strand.

Each human chromosome is replicated from a single origin of replication.

DNA replication in humans proceeds in a unidirectional manner from the origin.

DNA replication in humans occurs only during mitosis and not during meiosis.

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Verified step by step guidance

Step 1: Understand the concept of DNA replication in humans. DNA replication is the process by which a cell duplicates its DNA before cell division, ensuring each daughter cell receives an identical copy.

Step 2: Recall that DNA replication is semi-conservative, meaning each new DNA molecule consists of one original (parental) strand and one newly synthesized strand. This is a fundamental principle confirmed by experiments such as the Meselson-Stahl experiment.

Step 3: Consider the origin of replication in human chromosomes. Each human chromosome contains multiple origins of replication, not just a single one, to allow the large genome to be copied efficiently.

Step 4: Examine the directionality of DNA replication. In humans, replication is bidirectional from each origin, meaning replication forks move outward in both directions, not unidirectional.

Step 5: Understand the timing of DNA replication. DNA replication occurs during the S phase of the cell cycle, which is part of interphase, not during mitosis or meiosis themselves. Both mitosis and meiosis are processes of cell division that follow DNA replication.