Multiple Choice
Which RNA polymerase is responsible for transcribing mRNA from eukaryotic structural genes?
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10. Transcription
Transcription in Eukaryotes
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Which of the following modifications occurs to the RNA polymerase tail in order to trigger it to elongate the transcript?
A
Methylation
B
Acetylation
C
Carboxylation
D
Phosphorylation
Verified step by step guidance1
Understand the role of RNA polymerase in transcription: RNA polymerase is an enzyme responsible for synthesizing RNA from a DNA template during the process of transcription.
Learn about the structure of RNA polymerase: It has a tail known as the C-terminal domain (CTD), which plays a crucial role in the regulation of transcription.
Explore the concept of post-translational modifications: These are chemical changes to a protein after it has been synthesized, which can affect its function.
Identify the specific modification related to transcription elongation: Phosphorylation is the addition of a phosphate group to a protein, which can alter its activity.
Connect phosphorylation to RNA polymerase function: The phosphorylation of the RNA polymerase tail (CTD) is a key modification that triggers the transition from transcription initiation to elongation, allowing the enzyme to proceed with RNA synthesis.
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