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Multiple Choice
Which of the following general transcription factors is responsible for binding to the TATA-Box
A
TFIIA
B
TFIIB
C
TFIID
D
TFIIH
Verified step by step guidance
1
Understand the role of general transcription factors in the process of transcription initiation. These factors are essential for the assembly of the transcription machinery at the promoter region of a gene.
Learn about the TATA box, a DNA sequence found in the promoter region of many genes. It is a crucial element for the binding of transcription factors and the initiation of transcription.
Identify the general transcription factor responsible for recognizing and binding to the TATA box. This factor is known as TFIID, which includes the TATA-binding protein (TBP) and several TBP-associated factors (TAFs).
Explore the function of TFIID in transcription initiation. TFIID binds to the TATA box, facilitating the recruitment of other transcription factors and RNA polymerase II to form the transcription initiation complex.
Review the roles of other general transcription factors such as TFIIA, TFIIB, and TFIIH. While they are involved in the transcription process, they do not directly bind to the TATA box like TFIID does.