Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

17. Mutation, Repair, and Recombination

DNA Repair

Genetics

17. Mutation, Repair, and Recombination

DNA Repair

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Multiple Choice

Which of the following repair pathways uses a methylated strand of DNA to correct DNA damage?

Base Excision Repair

Nucleotide Excision Repair

Mismatch Repair

Homologous Recombination

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Verified step by step guidance

Understand the concept of DNA methylation: DNA methylation involves the addition of a methyl group to the DNA molecule, typically at cytosine bases. This modification can affect gene expression and is used in certain DNA repair mechanisms.

Learn about the mismatch repair pathway: Mismatch repair is a system within the cell that corrects errors that occur during DNA replication, such as base mismatches or small insertion-deletion loops.

Explore how mismatch repair uses methylation: In bacteria, the mismatch repair system distinguishes the newly synthesized DNA strand from the template strand by recognizing methylation patterns. The template strand is methylated, while the newly synthesized strand is not, allowing the repair machinery to identify and correct errors on the new strand.

Compare mismatch repair with other repair pathways: Base excision repair and nucleotide excision repair do not use methylation to identify the correct strand. Instead, they focus on removing damaged bases or nucleotides and replacing them with the correct ones.

Recognize the role of homologous recombination: Homologous recombination is a repair mechanism that uses a homologous sequence as a template to repair double-strand breaks, but it does not involve methylation for strand discrimination.