Multiple Choice
Which of the following ways reciprocal translocated chromosomes are sorted produces viable gametes?
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6. Chromosomal Variation
Chromosomal Rearrangements: Translocations
Multiple Choice
How many chromosomes does a person who is a carrier for familial down syndrome caused by a robertsonian translocation have?
A
45
B
46
C
47
D
48
Verified step by step guidance1
Understand that familial Down syndrome can be caused by a Robertsonian translocation, which involves the fusion of two acrocentric chromosomes.
Recognize that in a typical human karyotype, there are 46 chromosomes, including 22 pairs of autosomes and 1 pair of sex chromosomes.
In a Robertsonian translocation, two acrocentric chromosomes fuse at the centromere, reducing the total chromosome count by one.
A carrier of familial Down syndrome has one chromosome pair replaced by a single translocated chromosome, resulting in a total of 45 chromosomes.
Consider that the carrier is phenotypically normal because they have the correct amount of genetic material, despite having fewer chromosomes.
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