6. Chromosomal Variation

Chromosomal Rearrangements: Translocations

Multiple Choice
Which type of chromosomal rearrangement occurs when part of a chromosome breaks off and attaches to a nonhomologous chromosome?
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Multiple Choice
Which of the following represents the chromosomal segregation into gametes after a reciprocal translocation caused by adjacent-1 segregation? N=Normal chromosome T = Tanslocated chromosome
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Multiple Choice
Which of the following ways reciprocal translocated chromosomes are sorted produces viable gametes?
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Multiple Choice
An individual heterozygous for a reciprocal translocation has the following chromosomes. Which chromosomes do the gametes receive after alternative segregation?
A B • C D E F G J K • L M N O P
A B • C D N O P J K • L M E F G
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Multiple Choice
An individual heterozygous for a reciprocal translocation has the following chromosomes. Which chromosomes do the gametes receive after adjacent-1 segregation?
A B • C D E F G J K • L M N O P
A B • C D N O P J K • L M E F G
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Multiple Choice
An individual heterozygous for a reciprocal translocation has the following chromosomes. Which chromosomes do the gametes receive after adjacent-2 segregation?
A B • C D E F G J K • L M N O P
A B • C D N O P J K • L M E F G
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Multiple Choice
How many chromosomes does a person who is a carrier for familial down syndrome caused by a robertsonian translocation have?
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Textbook Question
From the following list, identify the types of chromosome changes you expect to show phenotypic consequences.
Reciprocal balanced translocation
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Textbook Question
An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
MN • OPQRST
MN • OPQRjkl
cdef • ghijkl
cdef • ghiST
Among the three segregation patterns, which is least likely to occur? Why?
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Textbook Question
An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
      MN • OPQRST
      MN • OPQRjkl
      cdef • ghijkl
      cdef • ghiST
Identify the gametes produced by adjacent-2 segregation. Which if any of these gametes are viable?
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Textbook Question
An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
      MN • OPQRST
      MN • OPQRjkl
      cdef • ghijkl
      cdef • ghiST
Identify the gametes produced by adjacent-1 segregation. Which, if any, of these gametes are viable?
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Textbook Question
An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
      MN • OPQRST
      MN • OPQRjkl
      cdef • ghijkl
      cdef • ghiST
Identify the gametes produced by alternate segregation. Which, if any, of these gametes are viable?
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Textbook Question
An animal heterozygous for a reciprocal balanced translocation has the following chromosomes:
      MN • OPQRST
      MN • OPQRjkl
      cdef • ghijkl
      cdef • ghiST
Diagram the pairing of these chromosomes in prophase I.
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Textbook Question
A boy with Down syndrome (trisomy 21) has 46 chromosomes. His parents and his two older sisters have a normal phenotype, but each has 45 chromosomes.
What is the probability the next child of this couple will have a normal phenotype and have 46 chromosomes? Explain your answer.
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Textbook Question
A boy with Down syndrome (trisomy 21) has 46 chromosomes. His parents and his two older sisters have a normal phenotype, but each has 45 chromosomes.
What term best describes this kind of chromosome abnormality?
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