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Multiple Choice
Which of the following is NOT a method of mRNA modification?
A
5' cap
B
3' Poly-A tail
C
Methylation
D
Splicing
Verified step by step guidance
1
Understand the concept of mRNA modification: mRNA modification is a process that occurs in eukaryotic cells where the primary mRNA transcript undergoes several changes before it is translated into a protein.
Identify the common methods of mRNA modification: The primary methods include the addition of a 5' cap, the addition of a 3' Poly-A tail, and splicing.
Explain the 5' cap addition: This involves adding a modified guanine nucleotide to the 5' end of the mRNA, which helps protect the mRNA from degradation and assists in ribosome binding during translation.
Explain the 3' Poly-A tail addition: This involves adding a long chain of adenine nucleotides to the 3' end of the mRNA, which also helps protect the mRNA from degradation and aids in the export of the mRNA from the nucleus.
Explain splicing: This process involves the removal of non-coding sequences (introns) from the mRNA transcript and the joining of coding sequences (exons) to produce a mature mRNA molecule that can be translated into a protein.