Multiple Choice
In eukaryotic mRNA, sequences found in the mature mRNA are termed:
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10. Transcription
RNA Modification and Processing
Multiple Choice
Which of the following statements is true of eukaryotic pre-mRNA processing?
A
A 5′ cap is added to the pre-mRNA, introns are removed by the spliceosome, and a 3′ poly(A) tail is added.
B
Prokaryotic mRNAs are processed by addition of a 5′ cap and extensive splicing before translation begins.
C
Introns are removed from eukaryotic pre-mRNA by DNA polymerase during transcription.
D
Eukaryotic mRNAs typically receive a poly(A) tail at the 5′ end to protect against exonucleases.
Verified step by step guidance1
Understand that eukaryotic pre-mRNA processing involves several key modifications before the mRNA is mature and ready for translation.
Recall that a 5′ cap, which is a modified guanine nucleotide, is added to the 5′ end of the pre-mRNA to protect it from degradation and assist in ribosome binding.
Recognize that introns, which are non-coding sequences, are removed from the pre-mRNA by a complex called the spliceosome, resulting in a continuous coding sequence.
Know that a 3′ poly(A) tail, consisting of multiple adenine nucleotides, is added to the 3′ end of the pre-mRNA to increase stability and aid in nuclear export.
Evaluate the given statements by comparing them to these known facts about eukaryotic pre-mRNA processing to identify the true statement.
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