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1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

13. Gene Regulation in Eukaryotes

Overview of Eukaryotic Gene Regulation

Genetics

13. Gene Regulation in Eukaryotes

Overview of Eukaryotic Gene Regulation

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Multiple Choice

Drosophilia sex determination is controlled through which of the following mechanisms?

Alternative splicing of the dsx gene

Alternative splicing of sxl gene

Inactivation of dsx gene

Ratio of X chromosomes to Y chromosomes

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Verified step by step guidance

Understand that Drosophila sex determination involves a cascade of genetic interactions, primarily focusing on the Sex-lethal (Sxl), Transformer (Tra), and Doublesex (Dsx) genes.

Recognize that the Sxl gene is the master regulator in the sex determination pathway, which is activated in females (XX) and remains inactive in males (XY).

Learn that the Sxl gene controls the splicing of the transformer (tra) pre-mRNA, which is crucial for female development.

Identify that the tra gene, when properly spliced, produces a functional Tra protein that, along with Tra-2, regulates the alternative splicing of the dsx pre-mRNA.

Conclude that the alternative splicing of the dsx gene results in different Dsx protein isoforms, which determine the sexual phenotype of the fly: DsxF in females and DsxM in males.