Question 1

Which of the following statements best explains why carboxylic acids have higher boiling points than esters and alkanes of similar molecular weight?

Accepted Answer

Carboxylic acids can form strong hydrogen bonds with each other, increasing intermolecular forces.

Question 2

What is the correct IUPAC name for the compound with the following structure: $$\mathrm{CH_3CH(OH)CH(CH_3$)COOH}$$?

Accepted Answer

3-hydroxy-2-methylbutanoic acid

Question 3

Which functional group has the highest priority in IUPAC nomenclature when naming a molecule with multiple functional groups?

Accepted Answer

Carboxylic acid

Question 4

Which of the following compounds is most likely to be water-soluble and odorless?

Accepted Answer

A low-molecular-weight unsubstituted amide

Question 5

What is the product of the acid-catalyzed hydrolysis of ethyl formate ($$\mathrm{HCOOCH_2CH_3}$$)?

Accepted Answer

Formic acid and ethyl alcohol

Question 6

Which of the following best describes the effect of electronegative substituents (such as chlorine) on the acidity of carboxylic acids?

Accepted Answer

They increase acidity by stabilizing the carboxylate anion.

Question 7

Which of the following is the correct structure for butyl acetate?

Accepted Answer

$$\mathrm{CH_3COOCH_2CH_2CH_2CH_3}$$

Question 8

Which of the following statements about amides is TRUE?

Accepted Answer

Unsubstituted amides can form multiple hydrogen bonds and are generally solids.

Question 9

What is the product of the hydrolysis of N-ethylbutanamide ($$\mathrm{CH_3CH_2CH_2CONHCH_2CH_3}$$)?

Accepted Answer

Butanoic acid and ethylamine

Question 10

Which of the following is a correct description of saponification?

Accepted Answer

Base-catalyzed hydrolysis of an ester to produce a carboxylic acid salt and an alcohol

Question 11

Which of the following is the correct name for the compound $$\mathrm{CH_3CH_2COOH}$$?

Accepted Answer

Propanoic acid

Question 12

Which compound would be expected to have the lowest boiling point?

Accepted Answer

Methyl acetate (an ester)

Question 13

Which of the following is a correct statement about the hydrolysis of esters and amides?

Accepted Answer

Both esters and amides can be hydrolyzed to yield carboxylic acids and either alcohols or amines.

Question 14

Which of the following is the correct formula for the acetate ion formed from acetic acid?

Accepted Answer

$$\mathrm{CH_3COO^-}$$

Question 15

Which of the following best describes the process of phosphorylation in biochemistry?

Accepted Answer

Transfer of a phosphoryl group from one molecule to another

Question 16

Which of the following is a correct description of the structure of a phosphate ester?

Accepted Answer

A compound formed by reaction of an alcohol with phosphoric acid, containing a C-O-P linkage

Question 17

Which of the following is the correct name for the compound $$\mathrm{H_2C=CHCOOH}$$?

Accepted Answer

Propenoic acid

Question 18

Which of the following statements about the physical properties of carboxylic acids, esters, and amides is TRUE?

Accepted Answer

Carboxylic acids and unsubstituted or monosubstituted amides exhibit strong hydrogen bonding to one another.

Question 19

Which of the following is the correct product of the reaction between acetic acid and ammonia?

Accepted Answer

Acetamide and water

Carboxylic Acids and Their Derivatives: Properties, Nomenclature, Reactions, and Biological Importance

Study Guide - Practice Questions