Table of contents

1. A Review of General Chemistry5h 5m
2. Molecular Representations1h 14m
3. Acids and Bases2h 46m
4. Alkanes and Cycloalkanes4h 17m
5. Chirality3h 39m
6. Thermodynamics and Kinetics1h 22m
7. Substitution Reactions1h 48m
8. Elimination Reactions2h 30m
9. Alkenes and Alkynes2h 9m
10. Addition Reactions3h 19m
11. Radical Reactions1h 58m
12. Alcohols, Ethers, Epoxides and Thiols2h 42m
13. Alcohols and Carbonyl Compounds2h 17m
14. Synthetic Techniques1h 26m
15. Analytical Techniques:IR, NMR, Mass Spect7h 3m
16. Conjugated Systems6h 13m
17. Ultraviolet Spectroscopy51m
18. Aromaticity2h 34m
19. Reactions of Aromatics: EAS and Beyond5h 1m
20. Phenols55m
21. Aldehydes and Ketones: Nucleophilic Addition4h 56m
22. Carboxylic Acid Derivatives: NAS2h 51m
23. The Chemistry of Thioesters, Phophate Ester and Phosphate Anhydrides1h 10m
24. Enolate Chemistry: Reactions at the Alpha-Carbon1h 53m
25. Condensation Chemistry2h 9m
26. Amines1h 43m
27. Heterocycles2h 0m
28. Carbohydrates5h 53m
29. Amino Acids4h 20m
30. Peptides and Proteins2h 42m
31. Catalysis in Organic Reactions1h 30m
32. Lipids 2h 50m
33. The Organic Chemistry of Metabolic Pathways2h 52m
34. Nucleic Acids1h 32m
35. Transition Metals6h 14m
36. Synthetic Polymers1h 49m

2. Molecular Representations

How To Determine Solubility

Organic Chemistry

2. Molecular Representations

How To Determine Solubility

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Multiple Choice

Which factor is most important in determining the solubility of a compound in water?

Molecular weight of the compound

Polarity of the compound

Color of the compound

Presence of a chiral center

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Verified step by step guidance

Understand that solubility in water is primarily influenced by the ability of a compound to interact with water molecules. Water is a polar solvent, so it tends to dissolve polar substances well.

Recognize that polarity refers to the distribution of electrical charge over the atoms in a molecule. Polar molecules have regions of partial positive and negative charge, which can interact favorably with the polar water molecules.

Consider the molecular weight of a compound. While it can affect solubility, it is not as significant as polarity. Larger molecules may have more difficulty dissolving, but if they are polar, they can still be soluble.

Evaluate the color of a compound. This is generally unrelated to solubility. Color is often due to the presence of certain functional groups or conjugated systems, but it does not affect how a compound interacts with water.

Assess the presence of a chiral center. Chirality can influence the biological activity and physical properties of a compound, but it does not directly affect solubility in water. The key factor remains the polarity of the compound.