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Multiple Choice
The glycerol derived from lipolysis of a triglyceride molecule is converted into glycerol-3-phosphate followed by dihydroxyacetone phosphate. Which step does this dihydroxyacetone phosphate enter in terms of glycolysis?
A
Step 1
B
Step 3
C
Step 5
D
Step 10
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1
Understand that dihydroxyacetone phosphate (DHAP) is an intermediate in glycolysis, which is the metabolic pathway that converts glucose into pyruvate.
Recall that DHAP is formed from glycerol-3-phosphate, which is derived from glycerol, a product of triglyceride breakdown.
Recognize that DHAP is isomerized to glyceraldehyde-3-phosphate (G3P) by the enzyme triose phosphate isomerase in glycolysis.
Identify that the conversion of DHAP to G3P occurs in Step 5 of glycolysis, where both DHAP and G3P are interconvertible.
Conclude that the correct step in glycolysis where dihydroxyacetone phosphate enters is Step 5, as it is converted to glyceraldehyde-3-phosphate, which continues through the glycolytic pathway.