Without using pK_a values, pick out the more acidic compound in each pair. Explain your answer.
(a)

Identify the stronger acid in each pair. Explain your choice. Citing pK_a values is not an acceptable answer.

(a)

Without using pK_a values, pick out the least reactive (most stable) base in each pair. Explain your answer.

(a)

Without using pK_a values, pick out the least reactive (most stable) base in each pair. Explain your answer.

(c)

Which of the following indicated atoms would you expect to be most basic?

(a)

Without using pK_a values, pick out the more reactive (least stable) base in each pair. Explain your answer.

(a)

Tenormin, a member of the group of drugs known as beta-blockers, is used to treat high blood pressure and improve survival after a heart attack. It works by slowing down the heart to reduce its workload. Which atom in Tenormin is the most basic?

A carboxylic acid ( pK_a = 5) is 10¹¹ times more acidic than an alcohol (pK_a = 16). Why?

Compare the properties of propan-2-ol (I) and the hexafluoro analog (II).

(a) Compound II has almost triple the molecular weight of I, but II has a lower boiling point. Explain.