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Social Determinants of Health: Mechanisms, Pathways, and Inequality

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Social Determinants of Health: Concepts and Frameworks

Introduction to Social Determinants of Health (SDOH)

The social determinants of health (SDOH) are the non-medical factors that influence health outcomes. These include the conditions in which people are born, grow, live, work, and age, as well as the broader set of forces and systems shaping the conditions of daily life. SDOH are primary predictors of health outcomes, often outweighing the effects of individual behaviors such as smoking or diet.

  • Key SDOH: Early life, education, employment and working conditions, food security, geography, health care services, housing, income and its distribution, social exclusion, social safety net, unemployment and employment security.

  • Social Locations: Disability, gender, immigrant status, Indigenous ancestry, race.

Box 1.2: The Social Determinants of Health Framework

Upstream vs. Downstream Approaches

Addressing health requires moving beyond treating individual cases ('pulling people out of the river') to addressing root causes ('going upstream'). Upstream interventions focus on changing social, economic, and policy environments to prevent health problems before they occur.

Upstream and downstream interventions cartoon

Equality, Equity, and Reality in Health

Understanding the difference between equality (everyone gets the same resources), equity (resources are distributed based on need), and reality (systemic barriers persist) is crucial for addressing health disparities. True health equity requires removing structural barriers, not just equalizing resources.

Equality, Equity, Reality cartoon

Mechanisms and Pathways: How SDOH Affect Health

The Health Gradient

The health gradient illustrates how health outcomes improve with each step up the social ladder. Factors such as poverty, inadequate nutrition, lack of education, unemployment, and poor housing create cumulative health hazards that cannot be overcome by individual action alone.

The Health Gradient

Premature Mortality and Income Inequality

Income-related factors are a major cause of premature years of life lost in Canada. Diseases such as cardiovascular disease, cancers, and injuries are disproportionately higher among those with lower income.

Percentage of premature years of life lost to various causes Percentage of income-related premature years of life lost by disease

Relative Risk and Excess Deaths

Being poor is associated with a higher relative risk (RR) of dying from major diseases compared to being wealthy. The table below summarizes the RR and excess deaths for various diseases among Canadians.

Disease

RR1 Men

RR1 Women

Excess deaths (%) Men

Excess deaths (%) Women

Cardiovascular disease

1.67

1.53

19

18

Cancers

1.46

1.30

16

11

Diabetes

2.49

2.64

21

26

Respiratory disease

2.31

2.11

37

39

HIV/AIDS

3.57

11.40

18

30

Injuries

1.88

1.83

17

17

Table 1.1: Greater risk of dying associated with being poor

International Comparisons and Child Well-Being

OECD Rankings and Child Health

International comparisons show that countries with stronger social policies and lower inequality (e.g., Finland, Netherlands) have better health outcomes and child well-being. Canada performs well in academic skills but lags in mental health and equity.

Table 1.2: Finland, Canada, and US Rankings on Social Determinants of Health

Trends in Child Well-Being

Recent UNICEF reports highlight declining life satisfaction and rising mental health challenges among children in wealthy nations, including Canada. Overweight rates and suicide risks remain persistent issues, reflecting the ongoing impact of material and social stressors.

Overweight and Obesity in Children

Frameworks for Understanding SDOH

Materialist and Neo-Materialist Frameworks

Materialist frameworks focus on how objective living conditions (e.g., income, housing, employment) shape health. Neo-materialist perspectives emphasize the role of societal resource distribution and public investment in creating health equity.

  • Material advantage/disadvantage across the life course predicts health outcomes.

  • Health gradient: Stepwise differences in health by socioeconomic position.

  • Neo-materialist view: Societies with more equal distribution of resources and stronger public services have healthier populations.

Psychobiological Stress Response

Chronic stress from social disadvantage leads to allostatic load—the cumulative wear and tear on the body. This increases risks for cardiovascular disease, diabetes, and premature death.

  • Allostasis: The body's ability to maintain stability through change.

  • Allostatic load: Damage from repeated or prolonged stress responses.

Lifecourse Perspective

Health is shaped by early life experiences and accumulated conditions over time. Effects include:

  • Latent effects: Early exposures leave lasting biological imprints.

  • Pathway effects: Early conditions set trajectories for education, work, and health.

  • Cumulative effects: Disadvantages compound over time, even if circumstances improve later.

Social Comparison Perspective

Health inequalities arise not only from material deprivation but also from perceived social position. Feelings of shame, worthlessness, and envy can activate stress pathways, leading to poorer health even when basic needs are met.

Structural Inequities and Health

Gender, Race, and Disability

Structural inequities in gender, race, and disability status shape access to resources, employment, and health care. These inequities result in higher stress, reduced independence, and poorer health outcomes for marginalized groups.

Political Economy and Neoliberalism

Market-driven policies and globalization have led to reduced public resources, increased precarious work, and weakened social supports. These changes disproportionately harm disadvantaged groups and increase health inequalities.

Summary Table: Key International Indicators

Measure

Finland

Canada

US

% Living in poverty (2022)

3

18

34

Food security environment (2022)

1

7

34

Income inequality (2022)

7

14

36

Public social expenditure (2022)

8

30

34

Life expectancy (2022)

15

18

31

Child environmental well-being (2022)

5

28

37

Table 1.2: Finland, Canada, and US Rankings on Social Determinants of Health

Conclusion

Understanding and addressing the social determinants of health is essential for reducing health inequalities and improving population health. Effective interventions require upstream, equity-focused policies that address the root causes of disadvantage and invest in social supports for all.

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