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Multiple Choice
How is ATP used during muscle contraction?
A
ATP is used to convert actin into myosin.
B
ATP is required to initiate the release of acetylcholine at the neuromuscular junction.
C
ATP is used to pump calcium ions back into the sarcoplasmic reticulum.
D
ATP binds to myosin, allowing it to detach from actin after the power stroke.
Verified step by step guidance
1
Understand the role of ATP in muscle contraction: ATP is crucial for muscle contraction and relaxation. It provides the energy needed for various steps in the contraction cycle.
Identify the process of the power stroke: During muscle contraction, myosin heads bind to actin filaments, forming cross-bridges. The power stroke occurs when the myosin head pivots, pulling the actin filament toward the center of the sarcomere.
Recognize the role of ATP in detachment: After the power stroke, ATP binds to the myosin head. This binding causes a conformational change in the myosin, reducing its affinity for actin and allowing the myosin head to detach from the actin filament.
Understand ATP hydrolysis: Once ATP is bound to myosin, it is hydrolyzed to ADP and inorganic phosphate. This hydrolysis provides the energy needed to re-cock the myosin head, preparing it for the next cycle of binding and power stroke.
Learn about calcium ion regulation: ATP is also used to pump calcium ions back into the sarcoplasmic reticulum, which is essential for muscle relaxation. This process ensures that calcium ions are available for the next contraction cycle.