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Multiple Choice
What is the role of ATP in cross-bridge cycling during muscle contraction?
A
ATP binds to actin to initiate the power stroke.
B
ATP provides the energy needed to detach the myosin head from the actin filament.
C
ATP is responsible for the release of calcium ions from the sarcoplasmic reticulum.
D
ATP directly causes the myosin head to bind to actin.
Verified step by step guidance
1
Understand the structure of a muscle fiber, focusing on the sarcomere, which is the functional unit of muscle contraction. The sarcomere contains actin (thin filament) and myosin (thick filament) proteins.
Learn about the cross-bridge cycle, which is the process that leads to muscle contraction. This cycle involves the interaction between actin and myosin filaments.
Recognize the role of ATP in the cross-bridge cycle. ATP binds to the myosin head, causing it to detach from the actin filament. This is a crucial step in the cycle, allowing the myosin head to reset and prepare for another power stroke.
Understand that after ATP binds to the myosin head, it is hydrolyzed to ADP and inorganic phosphate (Pi). This hydrolysis provides the energy needed for the myosin head to return to its 'cocked' position, ready to bind to actin again.
Note that ATP is not responsible for the initial binding of myosin to actin or the release of calcium ions from the sarcoplasmic reticulum. Its primary role is to provide energy for detachment and re-cocking of the myosin head, facilitating repeated cycles of muscle contraction.