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Multiple Choice
What is the primary driving force (pressure) that produces glomerular filtration in the kidneys?
A
Blood colloid osmotic pressure
B
Glomerular hydrostatic pressure
C
Interstitial fluid pressure
D
Capsular hydrostatic pressure
Verified step by step guidance
1
Understand the concept of glomerular filtration: Glomerular filtration is the process by which the kidneys filter blood, removing waste products and excess substances to form urine. This occurs in the glomerulus, a network of capillaries within the nephron.
Identify the pressures involved in glomerular filtration: There are several pressures that influence filtration, including glomerular hydrostatic pressure (GHP), blood colloid osmotic pressure (BCOP), and capsular hydrostatic pressure (CHP). Each plays a role in determining the net filtration pressure.
Focus on glomerular hydrostatic pressure (GHP): This is the primary driving force for filtration. It is the pressure exerted by the blood within the glomerular capillaries, pushing water and solutes out of the blood and into the Bowman's capsule.
Compare GHP to other pressures: Blood colloid osmotic pressure (BCOP) opposes filtration by pulling water back into the capillaries due to the presence of plasma proteins. Capsular hydrostatic pressure (CHP) also opposes filtration by exerting pressure from the fluid already in the Bowman's capsule. However, GHP is typically higher and drives filtration.
Conclude the importance of GHP: Glomerular hydrostatic pressure is the dominant force that initiates filtration in the kidneys. It must overcome the opposing pressures (BCOP and CHP) to ensure effective filtration and urine formation.