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Multiple Choice
Which of the following is commonly used to decrease elevated potassium levels in patients with acute renal failure?
A
Furosemide
B
Erythropoietin
C
Calcium carbonate
D
Insulin with glucose
Verified step by step guidance
1
Understand the physiological context: Elevated potassium levels, known as hyperkalemia, can occur in patients with acute renal failure due to the kidneys' inability to excrete potassium effectively. Hyperkalemia can lead to dangerous cardiac arrhythmias, so it requires prompt management.
Review the mechanism of action for insulin with glucose: Insulin facilitates the uptake of potassium into cells by stimulating the sodium-potassium ATPase pump. Administering glucose alongside insulin prevents hypoglycemia, which could occur due to insulin's effect on blood sugar levels.
Compare the other options: Furosemide is a loop diuretic that can help excrete potassium through urine, but it is not as rapid in action as insulin with glucose. Erythropoietin is used to stimulate red blood cell production and does not affect potassium levels. Calcium carbonate is used to manage hyperphosphatemia and does not directly lower potassium levels.
Explain why insulin with glucose is preferred: Insulin with glucose is commonly used in acute settings because it rapidly shifts potassium from the extracellular space into cells, effectively lowering serum potassium levels temporarily while other measures (like dialysis) are prepared.
Highlight the importance of monitoring: After administering insulin with glucose, continuous monitoring of potassium levels and cardiac function is essential to ensure the patient remains stable and to prevent rebound hyperkalemia.