Table of contents

1. Introduction to Anatomy & Physiology5h 43m
2. Cell Chemistry & Cell Components12h 36m
3. Energy & Cell Processes10h 6m
4. Tissues & Histology10h 3m
5. Integumentary System2h 20m
6. Bones & Skeletal Tissue2h 16m
7. The Skeletal System2h 35m
8. Joints2h 17m
9. Muscle Tissue2h 33m
10. Muscles1h 11m
11. Nervous Tissue and Nervous System1h 35m
12. The Central Nervous System1h 6m
- Introduction to the Central Nervous System
  18m
- The Cerebrum
  48m
13. The Peripheral Nervous System1h 26m
14. The Autonomic Nervous System1h 38m
15. The Special Senses2h 41m
16. The Endocrine System2h 48m
17. The Blood3h 22m
18. The Heart3h 42m
19. The Blood Vessels3h 35m
20. The Lymphatic System3h 16m
21. The Immune System14h 37m
22. The Respiratory System3h 20m
23. The Digestive System2h 5m
24. Metabolism and Nutrition4h 0m
25. The Urinary System2h 39m
26. Fluid and Electrolyte Balance, Acid Base Balance37m
27. The Reproductive System2h 5m
28. Human Development1h 21m
29. Heredity3h 32m

25. The Urinary System

Renal Physiology: Overview

Anatomy & Physiology

25. The Urinary System

Renal Physiology: Overview

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Multiple Choice

The glomerular filtration rate (GFR) is considered the best measure of renal function. Which of the following is commonly used to estimate GFR in clinical practice?

Serum creatinine

Serum albumin

Urine glucose

Blood urea nitrogen (BUN)

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Verified step by step guidance

Understand the concept of glomerular filtration rate (GFR): GFR is a measure of how well the kidneys filter blood, removing waste and excess substances. It is a critical indicator of renal function.

Recognize the role of serum creatinine: Serum creatinine is a waste product of muscle metabolism that is filtered by the kidneys. Its levels in the blood are commonly used to estimate GFR because they reflect kidney filtration efficiency.

Eliminate incorrect options: Serum albumin, urine glucose, and blood urea nitrogen (BUN) are not direct measures of GFR. While BUN can provide some information about kidney function, it is influenced by factors like hydration and protein intake, making it less reliable for estimating GFR.

Learn about the formula used in clinical practice: GFR is often estimated using equations like the Modification of Diet in Renal Disease (MDRD) or Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula, which incorporate serum creatinine levels along with factors like age, sex, and race.

Understand why serum creatinine is preferred: Serum creatinine is widely used because it is easy to measure, cost-effective, and provides a reliable estimate of GFR when used in conjunction with appropriate formulas.