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Multiple Choice
Which of the following does not occur during the citric acid cycle?
A
Release of carbon dioxide
B
Formation of FADH2
C
Oxidation of NADH to NAD+
D
Production of ATP
Verified step by step guidance
1
Understand the citric acid cycle: The citric acid cycle, also known as the Krebs cycle, is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins.
Identify the key processes in the citric acid cycle: During the cycle, acetyl-CoA is oxidized, carbon dioxide is released, and high-energy electron carriers such as NADH and FADH2 are produced. Additionally, a small amount of ATP (or GTP) is generated.
Examine the role of NADH and FADH2: In the citric acid cycle, NAD+ is reduced to form NADH, and FAD is reduced to form FADH2. These molecules carry electrons to the electron transport chain for further energy production.
Clarify the oxidation and reduction processes: Oxidation refers to the loss of electrons, while reduction refers to the gain of electrons. In the citric acid cycle, NAD+ is reduced to NADH, not oxidized.
Determine the incorrect statement: The statement 'Oxidation of NADH to NAD+' is incorrect in the context of the citric acid cycle, as NADH is not oxidized back to NAD+ during this cycle. Instead, NAD+ is reduced to NADH.