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Multiple Choice
Which class of MHC proteins presents exogenous antigens?
A
MHC Class IV
B
MHC Class III
C
MHC Class II
D
MHC Class I
Verified step by step guidance
1
Understand the role of Major Histocompatibility Complex (MHC) proteins in the immune system. MHC proteins are crucial for the presentation of antigens to T cells, which is a key step in the immune response.
Differentiate between the classes of MHC proteins. MHC Class I proteins present endogenous antigens, typically from within the cell, to CD8+ T cells. These are usually antigens from viruses or intracellular pathogens.
Learn about MHC Class II proteins. These proteins present exogenous antigens, which are antigens that originate outside the cell, to CD4+ T helper cells. This process is essential for initiating the immune response against extracellular pathogens.
Recognize that MHC Class III proteins are not involved in antigen presentation. Instead, they are associated with other immune functions, such as the production of certain components of the complement system.
Conclude that MHC Class II proteins are responsible for presenting exogenous antigens, as they are specifically designed to interact with CD4+ T helper cells to facilitate the immune response against pathogens that are outside the cells.