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Multiple Choice
Where are Major Histocompatibility Complex (MHC) molecules located on a cell?
A
In the cell nucleus
B
On the cell membrane
C
In the cytoplasm
D
In the mitochondria
Verified step by step guidance
1
Understand the role of Major Histocompatibility Complex (MHC) molecules: MHC molecules are crucial for the immune system to recognize foreign molecules in vertebrates, which helps in distinguishing self from non-self.
Identify the types of MHC molecules: There are two main classes of MHC molecules, Class I and Class II. Class I MHC molecules are present on almost all nucleated cells, while Class II MHC molecules are primarily on antigen-presenting cells.
Determine the location of MHC molecules: MHC molecules are located on the cell membrane. This positioning allows them to present peptide fragments to T cells, which is essential for immune response activation.
Consider the function of MHC molecules: By being on the cell membrane, MHC molecules can interact with T cells, facilitating the immune system's ability to detect and respond to pathogens.
Review the incorrect options: MHC molecules are not located in the cell nucleus, cytoplasm, or mitochondria, as these locations would not allow them to perform their function of presenting antigens to T cells.