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Multiple Choice
Which proteins on the antigen-presenting cell are recognized by the helper T-cell?
A
MHC Class I molecules
B
CD8 molecules
C
B-cell receptors
D
MHC Class II molecules
Verified step by step guidance
1
Understand the role of antigen-presenting cells (APCs) in the immune system. APCs are responsible for displaying antigens to T-cells, which is crucial for initiating an immune response.
Recognize the types of major histocompatibility complex (MHC) molecules. MHC molecules are proteins on the surface of cells that present antigen fragments to T-cells. There are two main classes: MHC Class I and MHC Class II.
Identify the specific interaction between helper T-cells and MHC molecules. Helper T-cells, also known as CD4+ T-cells, specifically recognize antigens presented by MHC Class II molecules on APCs.
Differentiate between the roles of CD8 molecules and CD4 molecules. CD8 molecules are found on cytotoxic T-cells and interact with MHC Class I molecules, whereas CD4 molecules are found on helper T-cells and interact with MHC Class II molecules.
Conclude that the proteins recognized by helper T-cells on antigen-presenting cells are MHC Class II molecules, which are essential for the activation of these T-cells in the immune response.