Multiple Choice
Class II MHC proteins are found on which of the following cell types?
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21. The Immune System
Major Histocompatibility Complex Molecules
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Which of the following are true of Class I Major Histocompatibility Complex (MHC) molecules?
A
They are only expressed on antigen-presenting cells.
B
They are expressed on all nucleated cells except neurons.
C
They present antigens to CD4+ T cells.
D
They present antigens to CD8+ T cells.
Verified step by step guidance1
Understand the role of Class I Major Histocompatibility Complex (MHC) molecules: They are crucial for the immune system to recognize cells that are infected with viruses or have become cancerous.
Identify the types of cells that express Class I MHC molecules: These molecules are expressed on all nucleated cells, which means any cell with a nucleus, except for neurons in some cases.
Differentiate between Class I and Class II MHC molecules: Class I MHC molecules present antigens to CD8+ T cells, which are cytotoxic T cells, while Class II MHC molecules present antigens to CD4+ T cells, which are helper T cells.
Clarify the function of CD8+ T cells: These cells are responsible for directly killing infected or cancerous cells, and they recognize antigens presented by Class I MHC molecules.
Conclude which statements are true: Based on the understanding of Class I MHC molecules, the correct statement is that they present antigens to CD8+ T cells.
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