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Multiple Choice
An enzyme known as acetylcholinesterase is present in the synaptic cleft. What is its role?
A
To synthesize acetylcholine from acetate and choline.
B
To transport acetylcholine across the synaptic cleft.
C
To break down acetylcholine into acetate and choline.
D
To inhibit the release of acetylcholine from the presynaptic neuron.
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Verified step by step guidance
1
Understand the role of acetylcholinesterase: Acetylcholinesterase is an enzyme located in the synaptic cleft, which is the space between neurons at a synapse.
Identify the substrate: Acetylcholine is the neurotransmitter that acetylcholinesterase acts upon. It is released into the synaptic cleft to transmit signals between neurons.
Determine the action of acetylcholinesterase: The enzyme's primary function is to catalyze the breakdown of acetylcholine into acetate and choline, effectively terminating the signal transmission.
Recognize the importance of this process: By breaking down acetylcholine, acetylcholinesterase prevents continuous stimulation of the postsynaptic neuron, allowing the synapse to reset for the next signal.
Consider the consequences of enzyme inhibition: If acetylcholinesterase is inhibited, acetylcholine would accumulate in the synaptic cleft, potentially leading to prolonged stimulation of the postsynaptic neuron and disrupted neural communication.