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Multiple Choice
To which part of the centromere do mitotic spindle fibers attach during prometaphase?
A
Centrosome
B
Kinetochore
C
Chromatid
D
Telomere
Verified step by step guidance
1
Understand the context of the problem: During cell division, specifically mitosis, the mitotic spindle fibers play a crucial role in separating chromosomes into daughter cells.
Identify the key components involved: The centromere is the region of a chromosome where the two sister chromatids are joined. The kinetochore is a protein structure on the centromere that serves as the attachment site for spindle fibers.
Clarify the function of the kinetochore: During prometaphase, the spindle fibers attach to the kinetochores, which are located on the centromeres of the chromosomes. This attachment is essential for the movement and alignment of chromosomes during mitosis.
Differentiate between the terms: The centrosome is the microtubule-organizing center, not the attachment site for spindle fibers on chromosomes. Chromatids are the individual strands of a chromosome, and telomeres are the ends of chromosomes, neither of which are involved in spindle fiber attachment.
Conclude with the correct answer: The mitotic spindle fibers attach to the kinetochore during prometaphase, facilitating the proper segregation of chromosomes.