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Multiple Choice
How do nonsteroid hormones differ from steroid hormones in their mechanism of action?
A
Nonsteroid hormones are synthesized from cholesterol, while steroid hormones are derived from amino acids.
B
Nonsteroid hormones bind to receptors on the cell surface, while steroid hormones enter the cell and bind to intracellular receptors.
C
Nonsteroid hormones directly activate genes, while steroid hormones use second messengers.
D
Nonsteroid hormones are lipid-soluble and can pass through the cell membrane, while steroid hormones are water-soluble and cannot.
Verified step by step guidance
1
Identify the chemical nature of nonsteroid and steroid hormones: Nonsteroid hormones are typically derived from amino acids, while steroid hormones are synthesized from cholesterol.
Understand the solubility properties: Nonsteroid hormones are generally water-soluble, meaning they cannot easily pass through the lipid bilayer of the cell membrane. In contrast, steroid hormones are lipid-soluble, allowing them to pass through the cell membrane.
Examine the mechanism of action for nonsteroid hormones: Since they are water-soluble, nonsteroid hormones bind to specific receptors on the surface of the target cell. This binding triggers a cascade of intracellular events often involving second messengers, such as cyclic AMP (cAMP), to relay the signal inside the cell.
Explore the mechanism of action for steroid hormones: Being lipid-soluble, steroid hormones can diffuse through the cell membrane and bind to intracellular receptors, typically located in the cytoplasm or nucleus. This hormone-receptor complex then directly interacts with the cell's DNA to regulate gene expression.
Compare the outcomes of hormone-receptor interactions: Nonsteroid hormones primarily use second messengers to exert their effects, leading to a rapid but often short-lived response. Steroid hormones, by directly influencing gene expression, tend to have longer-lasting effects on the target cell's function.