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Ch. 27 Fluids & Electrolytes
Martini - Fundamentals of Anatomy & Physiology 11th Edition
Martini, Nath, Bartholomew11th EditionFundamentals of Anatomy & PhysiologyISBN: 9780136874089Not the one you use?Change textbook
Chapter 26, Problem 27

Dan has been lost in the desert for 2 days with very little water. As a result of this exposure, you would expect to observe which of the following? 
(a) Increased ADH levels
(b) Decreased blood osmolarity
(c) Normal urine production
(d) Increased blood volume
(e) Cells enlarged with fluid

Verified step by step guidance
1
Step 1: Understand the physiological context. Dan has been without much water for 2 days, which means his body is likely experiencing dehydration.
Step 2: Recall the role of Antidiuretic Hormone (ADH). ADH is released by the posterior pituitary gland in response to increased blood osmolarity (concentration of solutes in the blood) to conserve water by reducing urine output.
Step 3: Analyze the expected changes in blood osmolarity. With dehydration, water loss exceeds solute loss, so blood osmolarity increases rather than decreases.
Step 4: Consider urine production. Due to increased ADH, the kidneys will conserve water, leading to decreased urine volume, not normal urine production.
Step 5: Evaluate blood volume and cell size. Dehydration causes blood volume to decrease and cells to shrink as water moves out of cells to balance osmolarity, so cells would not enlarge with fluid.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Antidiuretic Hormone (ADH) Function

ADH is a hormone that helps the body conserve water by reducing urine output. When the body is dehydrated, ADH levels increase to promote water reabsorption in the kidneys, concentrating the urine and maintaining blood volume.
Recommended video:
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Review of Major Hormones

Blood Osmolarity and Hydration Status

Blood osmolarity measures the concentration of solutes in the blood. Dehydration increases blood osmolarity because of water loss, signaling the body to retain water and restore balance through mechanisms like ADH release.
Recommended video:
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Osmosis and Osmolarity

Cellular Fluid Balance During Dehydration

In dehydration, extracellular fluid becomes more concentrated, causing water to move out of cells by osmosis. This results in cell shrinkage rather than enlargement, as cells lose water to balance osmotic pressure.
Recommended video:
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Osmoregulation and Nitrogenous Waste
Related Practice
Textbook Question

Exercise physiologists recommend that adequate amounts of fluid be ingested before, during, and after exercise. Why is fluid replacement during extensive sweating important?

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Textbook Question

Mary, a nursing student, has been caring for burn patients. She notices that they consistently show elevated levels of potassium in their urine and wonders why. What would you tell her?

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Textbook Question

Yuka is dehydrated, so her physician prescribes intravenous fluids. The attending nurse becomes distracted and erroneously gives Yuka a hypertonic glucose solution instead of normal saline. What effect will this mistake have on Yuka’s plasma ADH levels and urine volume?

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Textbook Question

After falling into an abandoned stone quarry filled with water and nearly drowning, a young boy is rescued. In assessing his condition, rescuers find that his body fluids have high PCO₂ and lactate levels and low PO₂ levels. Identify the underlying problem and recommend the necessary treatment to restore homeostatic conditions.

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Textbook Question

The most recent advice from medical and nutritional experts is to monitor one’s intake of salt so that it does not exceed the amount needed to maintain a constant ECF volume. What effect does excessive salt ingestion have on blood pressure?

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Textbook Question

While visiting a foreign country, Milly inadvertently drinks some water, even though she had been advised not to. She contracts an intestinal disease that causes severe diarrhea. How would you expect her condition to affect her blood pH, urine pH, and pattern of ventilation?

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