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Multiple Choice
Which of the following is not associated with the killing mechanism of a cytotoxic T cell?
A
Granzymes
B
Antibody production
C
Perforin release
D
Fas ligand interaction
Verified step by step guidance
1
Understand the role of cytotoxic T cells: Cytotoxic T cells are a type of immune cell that are primarily responsible for killing cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways.
Identify the mechanisms used by cytotoxic T cells: These cells use several mechanisms to induce cell death, including the release of perforin and granzymes, and the interaction with Fas ligand.
Explain perforin and granzymes: Perforin is a protein that forms pores in the target cell's membrane, allowing granzymes, which are serine proteases, to enter the cell and trigger apoptosis (programmed cell death).
Describe Fas ligand interaction: Fas ligand is a protein that binds to the Fas receptor on the surface of target cells, initiating a cascade that leads to apoptosis.
Clarify the role of antibodies: Antibody production is a function of B cells, not cytotoxic T cells. Cytotoxic T cells do not produce antibodies; instead, they directly kill target cells through the mechanisms described above.