Multiple Choice
The main difference between hormones that have intracellular receptors and those that have cell membrane receptors is that the former tend to be _______:
12. Biosignaling
Lipid Hormone Signaling
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Upon secretion, a chemical messenger (hormone) binds its receptors on other cells that were nearby. The hormone was secreted in such low concentration that it did not have any effect on distant cells, even though those distant cells had the appropriate receptors. We would best classify this hormone as a(n):
A
Endocrine hormone.
B
Paracrine hormone.
C
Autocrine hormone.
D
Both an autocrine hormone and an endocrine hormone.
Verified step by step guidance1
Understand the definitions of different types of hormones: Endocrine hormones are secreted into the bloodstream and can affect distant cells. Paracrine hormones affect nearby cells. Autocrine hormones affect the cell that secreted them.
Identify the key characteristic of the hormone in the problem: It affects nearby cells but not distant ones, even though distant cells have the appropriate receptors.
Relate the hormone's behavior to the definitions: Since the hormone affects nearby cells, it fits the definition of a paracrine hormone.
Consider why it is not an endocrine hormone: Endocrine hormones would affect distant cells, which is not the case here.
Evaluate the possibility of it being an autocrine hormone: The problem does not mention the hormone affecting the cell that secreted it, so it is not classified as autocrine.
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