Multiple Choice
What is the major difference between paracrine and endocrine signaling?
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12. Biosignaling
Lipid Hormone Signaling
Multiple Choice
In the context of lipid hormone signaling, which of the following hormones is a peptide hormone (rather than a lipid-derived steroid or eicosanoid)?
A
Prostaglandin
B
Insulin
C
Estradiol
D
Cortisol
Verified step by step guidance1
Understand the classification of hormones based on their chemical nature: peptide hormones are made of amino acids, steroid hormones are derived from cholesterol (lipid-based), and eicosanoids are lipid-derived signaling molecules from fatty acids.
Identify the hormones listed: Prostaglandin E2 is an eicosanoid, Estradiol and Cortisol are steroid hormones, and Insulin is a peptide hormone.
Recall that peptide hormones like Insulin are synthesized as polypeptides and act through membrane receptors, unlike steroid hormones which pass through the cell membrane to interact with intracellular receptors.
Confirm that Prostaglandin E2, Estradiol, and Cortisol are all lipid-derived molecules, while Insulin is the only peptide hormone among the options.
Conclude that Insulin is the peptide hormone in the list, distinguishing it from the lipid-derived steroid and eicosanoid hormones.
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