Multiple Choice
In glycolysis, the starting molecule (initial substrate) is which of the following?
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Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Glycolysis 1
Multiple Choice
In the glycolytic pathway, what are the net products obtained from the conversion of one molecule of glucose to two molecules of pyruvate under aerobic conditions?
A
, , and (net)
B
, , and (net)
C
, , and (net), plus and
D
, , and (net)
Verified step by step guidance1
Recall that glycolysis converts one molecule of glucose (a 6-carbon sugar) into two molecules of pyruvate (each with 3 carbons). This is the fundamental transformation in the pathway.
Identify the key energy carriers involved: ATP and NADH. Glycolysis consumes ATP initially but produces more ATP later, resulting in a net gain. It also reduces NAD+ to NADH during the oxidation steps.
Write the overall net reaction of glycolysis, which includes the substrates and products: glucose, ATP, ADP, NAD+, NADH, pyruvate, and protons (H+).
Determine the net ATP produced by subtracting the ATP used in the early steps from the ATP generated in the later steps. Glycolysis uses 2 ATP molecules and produces 4 ATP molecules, so the net ATP is 2.
Summarize the net products from one glucose molecule: 2 pyruvate molecules, 2 NADH molecules, and 2 ATP molecules (net), along with 2 molecules of water (H2O) and 2 protons (H+) released during the process.
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