Multiple Choice
During glycolysis (per molecule of glucose), how many ATP molecules are produced on a net basis?
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Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Glycolysis 1
Multiple Choice
During glycolysis (from one molecule of glucose to two molecules of pyruvate), what is the net gain of ATP per glucose molecule?
A
2 ATP
B
4 ATP
C
6 ATP
D
0 ATP
Verified step by step guidance1
Recall that glycolysis converts one molecule of glucose into two molecules of pyruvate through a series of enzymatic reactions.
Identify the ATP investment phase: In the early steps of glycolysis, 2 ATP molecules are consumed to phosphorylate glucose and its intermediates.
Identify the ATP payoff phase: Later in glycolysis, 4 ATP molecules are produced by substrate-level phosphorylation when intermediates are converted to pyruvate.
Calculate the net ATP gain by subtracting the ATP invested from the ATP produced: Net ATP = ATP produced - ATP consumed.
Conclude that the net gain of ATP per glucose molecule during glycolysis is 2 ATP.
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