Multiple Choice
In oxidative phosphorylation, when is ________, it becomes .
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Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Oxidative Phosphorylation 1
Multiple Choice
In aerobic metabolism, which of the following processes produces the most ATP per molecule of glucose?
A
Fermentation (e.g., lactate production)
B
Substrate-level phosphorylation in the citric acid (TCA) cycle (GTP/ATP formation)
C
Substrate-level phosphorylation in glycolysis
D
Oxidative phosphorylation (electron transport chain coupled to ATP synthase)
Verified step by step guidance1
Step 1: Understand the context of ATP production in aerobic metabolism. Glucose is metabolized through several pathways, including glycolysis, the citric acid cycle (TCA cycle), and oxidative phosphorylation, each contributing differently to ATP yield.
Step 2: Identify the ATP yield from substrate-level phosphorylation in glycolysis. This process directly produces a small amount of ATP by transferring a phosphate group to ADP, typically yielding 2 ATP molecules per glucose.
Step 3: Examine substrate-level phosphorylation in the citric acid cycle. Here, GTP (which can be converted to ATP) is produced directly, but the amount per glucose molecule is relatively low, usually 2 ATP equivalents per glucose.
Step 4: Consider fermentation processes like lactate production. Fermentation regenerates NAD+ but produces no additional ATP beyond the small amount generated in glycolysis, so it yields minimal ATP per glucose.
Step 5: Analyze oxidative phosphorylation, which occurs in the electron transport chain coupled to ATP synthase. This process uses electrons from NADH and FADH2 to create a proton gradient that drives ATP synthesis, producing the majority of ATP per glucose molecule in aerobic metabolism.
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