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Multiple Choice
In cellular respiration, which stage produces the greatest amount of ATP per glucose molecule in aerobic conditions?
A
Oxidative phosphorylation (electron transport chain and chemiosmosis)
B
Pyruvate oxidation (conversion of pyruvate to acetyl-CoA)
C
Citric acid cycle (Krebs cycle)
D
Glycolysis
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Verified step by step guidance
1
Step 1: Understand the stages of cellular respiration under aerobic conditions: Glycolysis, Pyruvate Oxidation, Citric Acid Cycle (Krebs Cycle), and Oxidative Phosphorylation (Electron Transport Chain and Chemiosmosis).
Step 2: Recall the ATP yield from each stage per glucose molecule: Glycolysis produces a small amount of ATP directly, Pyruvate Oxidation does not produce ATP directly but generates electron carriers, the Citric Acid Cycle produces some ATP and electron carriers, and Oxidative Phosphorylation uses these electron carriers to generate the majority of ATP.
Step 3: Recognize that Oxidative Phosphorylation involves the electron transport chain creating a proton gradient across the mitochondrial membrane, which drives ATP synthesis via chemiosmosis.
Step 4: Compare the ATP yields quantitatively: Glycolysis yields 2 ATP, Citric Acid Cycle yields 2 ATP, and Oxidative Phosphorylation yields approximately 26-28 ATP per glucose molecule.
Step 5: Conclude that Oxidative Phosphorylation produces the greatest amount of ATP per glucose molecule during aerobic respiration.