Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

4. Protein Structure

Peptide Bond

Biochemistry

4. Protein Structure

Peptide Bond

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Multiple Choice

What type of bond connects one amino acid to another in a polypeptide chain?

Disulfide bond

Peptide bond

Ionic bond

Hydrogen bond

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Verified step by step guidance

Understand the structure of amino acids: Amino acids are the building blocks of proteins, and each amino acid has an amino group (-NH₂), a carboxyl group (-COOH), and a unique side chain (R group).

Learn how amino acids are linked: Amino acids are connected through a condensation reaction (also called dehydration synthesis), where the carboxyl group of one amino acid reacts with the amino group of another amino acid.

Identify the bond formed: During the condensation reaction, a molecule of water (H₂O) is removed, and a covalent bond called a peptide bond is formed between the carbon of the carboxyl group and the nitrogen of the amino group.

Understand the significance of peptide bonds: Peptide bonds are the primary linkage in polypeptide chains, which are the structural basis of proteins. This bond is strong and stable, ensuring the integrity of the protein structure.

Differentiate peptide bonds from other bonds: Disulfide bonds, ionic bonds, and hydrogen bonds are also important in protein structure but serve different roles. Disulfide bonds stabilize tertiary and quaternary structures, ionic bonds occur between charged side chains, and hydrogen bonds contribute to secondary structures like alpha helices and beta sheets.